Research Facility
KFRC has excellent research facilities that support advanced scientific work across diverse fields.. The availability of specialized labs, advanced equipment, and a multidisciplinary environment enables KFRC to conduct high-quality research with translational applications.
Stem Cell Laboratory:
It is equipped for advanced research in regenerative medicine and stem cell biology. It is used for isolation, culture, and expansion of mesenchymal stem cells (MSCs) and other progenitor cell types and check for differentiation protocols for generating specialized cell types like osteocytes, adipocytes, and chondrocytes. Develop assays for characterizing stem cell markers and assessing pluripotency using flow cytometry and immunostaining. Cryopreservation systems for long-term storage of stem cell lines. We conduct all research related to regenerative therapies for degenerative diseases and injury repair and development of cell-based therapies and personalized medicine approaches.
Cell Culture Laboratory
- It provides a sterile and controlled environment for studying various cell lines and conducting experiments in cellular biology.
- Biosafety cabinets (Class II) for aseptic handling, CO₂ incubators to maintain optimal conditions for cell growth, High-resolution inverted microscopes for monitoring cell morphology and Equipment for media preparation and sterile filtration.
- Study of cancer cell lines for understanding tumor biology and drug response.
- Toxicity and immunogenicity testing of pharmaceutical compounds and vaccines on different cell types.
- Collaborative research in immunology, virology, and cell signaling pathways.
Molecular Biology & Proteomics Laboratory
- It is well-equipped for genetic, epigenetic, and transcriptomic analyses.
- PCR and quantitative real-time PCR (qPCR) machines for amplification and quantification of DNA/RNA.
- Gel electrophoresis systems for nucleic acid separation and analysis.
- Spectrophotometers and Nanodrop devices for assessing nucleic acid purity and concentration.
- Western blot apparatus for protein expression studies.
- Gene editing and manipulation using CRISPR-Cas9.
- Nucleic acid extractions and sequencing library preparation.
- High-throughput analysis of gene expression and mutation screening.
Imaging Facility
- It supports high-resolution visualization of biological samples for structural and functional studies.
- Fluorescence microscopes for studying labeled proteins, DNA, and cellular structures.
- Phase-contrast and live-cell imaging for advanced analysis
- Imaging software for detailed analysis and quantification of visual data.
- Cellular and subcellular imaging for cancer, stem cell, and neuroscience research.
- Real-time visualization of cell dynamics and interactions.
- Morphological assessments for developmental and disease studies.
Bioinformatics and Computational Biology Laboratory
- It integrates computational tools and techniques to analyze complex biological data.
- High-performance computing systems for data-intensive analyses.
- Software for next-generation sequencing (NGS) data analysis, genome annotation, and pathway analysis.
- Tools for proteomics, transcriptomics, and epigenomic studies.
- Analysis of large-scale datasets from genomics and transcriptomics experiments.
- Statistical modeling and simulation of biological systems.
- Integration of multi-omics data for biomarker discovery and therapeutic target identification.
General Research Equipment and Infrastructure
- Centrifuges: Cooling and high-speed for sample preparation and molecular separation.
- Refrigeration Units: -20°C, -40°C and -80°C freezers for sample and reagent storage.
- Spectrophotometers: For protein and nucleic acid quantification.
- Vortex Mixers and Plate Readers: For sample mixing and high-throughput analysis.
- Cryopreservation Units: For long-term storage of biological samples, including stem cells and cell lines.
- Autoclave: For sterilization and decontamination of biological materials.