Regenerative medicine has emerged as a new and most exciting field of life science in view of its potential clinical applications in many debilitating and non-curable diseases. This department holds the promise of repairing the damaged tissues and organs by stimulating the body’s own repair mechanisms. Regenerative medicine aims to revolutionize the treatment of disease by providing cures rather than treating symptoms. The aim of this department is to utilize the potential of stem cells in the management of non-curable diseases. Various approaches include stem cells in transplant therapy and disease modelling, tissue engineering to generate replacement tissues and organs, and the creation of animal models to study the fundamental and molecular basis of treatment. With the coordination of various clinicians of KIMS hospitals and collaboration with other reputed research institute, this department is actively involved in research programs like vascular disease, neurodegenerative diseases, orthopaedic conditions and in autoimmune disease.
The main objective of this department is to develop pioneering findings that could be exploited for improved detection, diagnosis, prognosis, prevention and treatment of cancer. The department initiates and integrates advances in fundamental research with translational application to cancer. It serves as an interface between academic and medical communities to promote understanding of cancer. This department focuses mainly on understanding cancer cell signalling, DNA repair mechanism, cancer stem cells, autophagy and chemoresistance. Furthermore, we are developing 3D exvivo cell culture model for studying cell-cell and drug-cell interactions.
Advances in Molecular Genetics have led to the detection of single genes that, when mutated, can cause diseases such as Wilson disease, autoimmune disease, heart disease, stroke, diabetes, and several kinds of cancer. The identification of disease-association genes and their signalling target will facilitate a better understanding of their function, as it paves the way towards effective diagnostics, therapeutics and preventative measures. Department of Molecular Genetics uses genomic analysis of patient samples to study inherited diseases and eventually utilizes cells as disease models to understand how gene mutations affect function, and to find ways to ameliorate the clinical outcome. Molecular Genetics research group focuses to create an interdisciplinary and cross-institution community and currently represents research on a wide range of biological problems.